Epigenetics: Tools, Diagnostics, Drugs and World Market

Published: August 2010

150 pages; Can be printed; fully searchable PDF format; TOC hyperlinks and Internet hyperlinks


SKU: TPR3180



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Description       Table of Contents      Tables and Figures


This broad and high-level report examines the emerging epigenetics market.  This world market includes important biomedical product areas that will have a powerful impact on healthcare delivery and personalized medicine. This business report analyzes key market segments such life science research tools, diagnostics and therapeutics.


Many people already know about DNA, genes and the human genome.  The DNA code defines the structure of who we are, our potential health and our characteristics that we pass on to our children.  Epigenetics refers to the second code of life and links environmental impacts to a person’s health. Epigenetic mechanisms signal how and when genes are activated or silenced.


This research study discusses the market for life science tools and technologies that support epigenetics R&D.  The report discusses important technologies, equipment and consumables including microarray, next-generation sequencing, PCR and other platforms.  Topics such as microRNA and human stem cells are lightly covered.


The report covers subjects including important epigenetic factors including DNA methylation, histone modifications and others.  The study discusses epigenetic biomarkers, commercial diagnostics and therapeutics that will foster personalized medicine.  The study highlights new epigenetic diagnostics. This research examines the current epigenetic therapeutics on the market and drugs in the clinical pipeline.  The report highlights major government grant initiatives such as the NIH’s ‘Roadmap Epigenomics Program’ initiatives, the EU’s ‘Epigenetic Network of Excellence’ and others.


This study discusses important epigenetics topics and provides the reader with key findings.  The data estimates that the worldwide epigenetics market value will reach multi-billions of dollars in 2010, with a strong double-digit growth rate. This report reviews the activities of 35 companies.  The study uses 39 figures and tables to illustrate the findings.  This study includes many valuable tables that help the reader scan the details of major trends, market segmentation, forecast, M&As, partnerships, grant funding, patents and so on.


This must-have report would benefit people with job titles including CEO, VPs, Director of Business Development, Research Directors, Entrepreneurs, Venture Capitalists, Investment Planners, Research Scientists, Consultants or Industry Analysts.



Table of Contents


1.The Epigenetics Market Landscape

   Epigenetics for R&D, Diagnostics & Therapeutics

     Brief History

     Understanding Epigenetic Mechanisms

     Epigenetics, Key Diseases and Demographics

     Tools & Technologies for Epigenetic R&D

     Epigenetic Diagnostic Tests

     Epigenetic-Based Therapeutics

   Key Business Applications

     Academic Research Applications

     Diagnostic Applications

     Therapeutic Applications

2.Major Alliances, M&As and IP

   Major Alliances and M&As In Epigenetics

     Definitions of Deal Types

     Summary of Major Epigenetics Alliances and M&As

     Alliance and M&A Data Tables

   Patents, Business Development and Challenges

     Highlights of Companies That Own IP Involving Epigenetic


     Valuations of Epigenetic Technologies and Products

     Business Development Challenges

     Patent Challenges

3.Epigenetics Market Forecast

   Epigenetics Product Market Size, 2008~2013

   Epigenetic Market by Product Segments

     Epigenetic R&D Tools and Technologies Segments

     Epigenetic Diagnostics Segments

     Epigenetic Therapeutics Segments

     WW Epigenetic Market By Vendor Product Shares, 2008 & 2013

   Market by Major Diseases

     Cancer Segment

     Neuro-psychological (CNS) Segment

     Infectious Disease Segment

     Respiratory Segment

     Reproductive Disease Segment

     The ‘Others’ Segment

   Epigenetic Market by R&D Developer Segments

     Academic/Gov. Basic Life Science R&D Sub-segments

     Diagnostics Developer Segments

     Pharma/ Biotech Rx/Tx Developer Segments

   Epigenetics Market by WW Regions

     North America


     Japan/ Asia Pacific


4.Selected Companies Working in Epigenetics

   454 Life Sciences (Roche)

   Abcam plc

   Active Motif, Inc.

   Affymetrix, Inc.

   Agilent Technologies, Inc., BAM/LS

   Applied Biosystems Group

   AVIVA Systems Biology


   Cogenics (Clinical Data)

   DNASTAR, Inc.

   Epigenomics AG

   Epigentek, Inc.

   Epiontis GmbH

   Fluidigm Corporation

   GATC Biotech AG

   GeneGo, Inc.

   Genomatix Software GmbH

   GenomeQuest, Inc.

   Genpathway, Inc.

   Human Genetic Signatures Pty. Ltd.

   Illumina, Inc.


   Methylgene, Inc.

   MGI Pharma, Inc. (subsidiary of Eisai)


   OncoMethylome Sciences SA

   Orion Genomics LLC

   Qiagen  N.V.

   Regulus Therapeutics LLC

   Roche Nimblegen

   Rubicon Genomics, Inc.


   SeqWright, Inc.

   Sigma-Aldrich Co.

   Zymo Research Corp.

5.Findings and Conclusions

   Epigenetics Market Future Direction

     Analytical Tools for Epigenetic R&D

         Commercial DNA Microarrays, ChIP on Chip and


         High-Throughput Sequencing and ChIP-Seq.

         Other Front Runner Technologies

     Consumables & Reagent Kits

     Commercial Diagnostic/ Test Services

     Therapeutics Involving Epigenetics

   Epigenetics Market Drivers and Restraints

     The US NIH Roadmap Epigenomics Program Initiatives

     The European Union Epigenetics Initiative

     M&A Deals Have Helped Epigenetic Product Companies

     FDA Approved Epigenetic Diagnostics Have Reached the


     FDA Approved Epigenetic Therapeutics Have Reached the


   Potential Business Opportunities

     Opportunities for American and European Companies

         Epigenetic Diagnostics

         Consider Other World Regions for Cost Savings or New


         Market into Asia for Business Opportunities

     Business Opportunities for Asian Companies


   Epigenetics Glossary

   Company Contacts

   Selected Grant Recipients for Epigenetics or Epigenomic


   About Takeda Pacific

   About the Authors


List of Tables


Table 1. Epigenetics Disease Demographics

Table 2. Summary of Major Alliances and M&As, 2005 to Oct.- 2008

Table 3. Alliances and M&As Jan. to Oct. 2008

Table 4. Major Alliances and M&As - 2007

Table 5. Major Alliances and M&As - 2006

Table 6. Major Alliances and M&As - 2005

Table 7. Epigenetics Related US Patents Issued to Orgs., 2007 to

        Oct.- 2008

Table 8. Valuations of Major M&As Involving Epigenetics.

Table 9. Total WW Epigenetic Product Market Revenues, 2008-2013

Table 10. WW Epigenetic Market By Vendor Products $M

Table 11. Epigenetic R&D Tools & Technologies Sub-segments $M

Table 12. Epigenetic Diagnostics Sub-segments $M

Table 13. Epigenetic Therapeutics Sub-segments $M

Table 14. WW Epigenetic Market By Vendor Product Shares, 2008 &


Table 15. WW Epigenetic Market By Leading Diseases $M

Table 16. Major Cancer Types Targeted in R&D and Shares

Table 17. WW Epigenetic Market By Developer Segments $M

Table 18. Academic/Gov. Basic Life Science R&D $M

Table 19. Diagnostics Developers

Table 20. Pharma/ Biotech Rx/Tx Developers

Table 21. WW Epigenetic Market By Regions $M

Table 22. High-Density Whole Genome Microarrays for Epigenetics

Table 23. High-Throughput DNA Sequencing For Epigenetics

Table 24. Other Technologies for Epigenetics

Table 25. Epigenetic Diagnostics Development Pipeline

Table 26. Therapeutics in Clinical Pipeline Involving Epigenetics

Table 27. NIH Roadmap Epigenomics Program Initiatives

Table 28. Glossary of Epigenetic Terms

Table 29. List of Company Contacts

Table 30. Selected NIH Grant Recipients and Epigenomic Projects


List of Figures


Figure 1. The Epigenetic Market Ecosystem

Figure 2. Highlights of Epigenetic Mechanisms

Figure 3. Growing Number of PubMed Articles About Epigenetics

Figure 4. Total WW Epigenetic Product Market Revenues, 2008-2013

Figure 5. WW Epigenetic Market By Vendor Products $M

Figure 6. WW Epigenetic Market By Product Market Shares, 2008 &


Figure 7. WW Epigenetic Market By Major Diseases $M

Figure 8. WW Epigenetic Market By Developer Segments $M

Figure 9. WW Epigenetic Market By Regions $M 


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